ZC3H12D

Across TCGA pan-cancer cohorts, ZC3H12D mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZC3H12D data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZC3H12D mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZC3H12D expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD and HNSC are the cancer types where ZC3H12D mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	1.000	0.885	.011	30	view →
HNSC	OS	Tertile	IV	1.000	0.677	.030	11	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZC3H12D–LUAD (DFS)

Open the LUAD breakdown →