ZC3H12C

Across TCGA patient cohorts, ZC3H12C protein abundance is significantly associated with the RNA expression of many other genes, with 4,839 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZC3H12C-associated genes across cancer lineages are MMP8, HNRNPA1L2, and TRPM8. Each is linked with ZC3H12C in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC3H12C-to-partner and partner-to-ZC3H12C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC3H12C versus MMP8 in PDAC, with a Pearson correlation of -0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC3H12C→partner) and Y-score (partner→ZC3H12C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MMP8 →	-1.415	-0.615	<.001	<.001	3	2
BRCA	HNRNPA1L2 →	-1.574	-3.282	<.001	<.001	3	2
CCRCC	TRPM8 →	-0.679	-0.208	.008	.003	3	2
BRCA	EEF1A1P5 →	-1.483	-3.367	<.001	<.001	3	2
LUAD	RNU1-146P →	-1.488	-0.318	.001	.001	3	2
PDAC	NBDY →	-0.378	-0.684	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,839 associations by consensus.

ZC3H12C vs MMP8 — PDAC

Explore this scatter interactively →