ZC2HC1C

Across TCGA patient cohorts, ZC2HC1C mutation is significantly associated with the RNA expression of many other genes, with 2,206 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZC2HC1C-associated genes across cancer lineages are RNU2-13P, C2orf69P4, and OR5H2. Each is linked with ZC2HC1C in more than 1 cancer types. Because this analysis shows association rather than direction, both ZC2HC1C-to-partner and partner-to-ZC2HC1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-13P grouped by ZC2HC1C-low versus ZC2HC1C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC2HC1C→partner) and Y-score (partner→ZC2HC1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU2-13P →	+0.198	+4.109	<.001	.007	3	2
COAD	C2orf69P4 →	+0.052	+5.934	<.001	<.001	3	2
BRCA	OR5H2 →	+0.059	+4.683	.001	.007	3	2
UCEC	GCAT →	+0.579	+3.536	.005	.002	3	2
UCEC	SLC25A17 →	+0.377	+2.246	.003	.005	3	2
UCEC	PPP2CB →	+0.589	+2.606	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,206 associations by consensus.

RNU2-13P by ZC2HC1C expression — COAD

Explore this box plot interactively →