ZC2HC1B

Across TCGA patient cohorts, ZC2HC1B protein abundance is significantly associated with the RNA expression of many other genes, with 6,783 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZC2HC1B-associated genes across cancer lineages are PIK3IP1, CFAP298, and RPL37P23. Each is linked with ZC2HC1B in more than 2 cancer types. Because this analysis shows association rather than direction, both ZC2HC1B-to-partner and partner-to-ZC2HC1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZC2HC1B versus PIK3IP1 in UCEC, with a Pearson correlation of -0.94.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZC2HC1B→partner) and Y-score (partner→ZC2HC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIK3IP1 →	-1.199	-1.399	.002	.002	3	3
UCEC	CFAP298 →	+0.970	+1.400	<.001	.002	3	3
UCEC	RPL37P23 →	+4.143	+1.400	<.001	.002	3	3
HNSC	SMC4 →	+0.631	+0.598	<.001	.001	3	3
HNSC	HEATR1 →	+0.521	+0.610	.001	.006	3	3
HNSC	DKC1 →	+0.708	+0.667	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,783 associations by consensus.

ZC2HC1B vs PIK3IP1 — UCEC

Explore this scatter interactively →