ZBTB8B

Across TCGA patient cohorts, ZBTB8B mutation is significantly associated with the RNA expression of many other genes, with 638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB8B-associated genes across cancer lineages are NKAIN1P1, NEK2P1, and TRAJ47. Each is linked with ZBTB8B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB8B-to-partner and partner-to-ZBTB8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKAIN1P1 grouped by ZBTB8B-low versus ZBTB8B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB8B→partner) and Y-score (partner→ZBTB8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NKAIN1P1 →	+0.099	+5.837	<.001	.001	3	2
CESC	NEK2P1 →	+0.062	+4.969	<.001	.004	3	2
BRCA	TRAJ47 →	+0.853	+5.062	<.001	.002	3	2
UCEC	TRIM54 →	+0.812	+3.263	<.001	.008	3	2
UCEC	RNU6-728P →	+0.183	+3.598	<.001	.002	3	2
UCEC	LINC01501 →	+0.175	+3.235	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 638 associations by consensus.

NKAIN1P1 by ZBTB8B expression — CESC

Explore this box plot interactively →