ZBTB8B

Across TCGA cell cohorts, ZBTB8B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,063 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZBTB8B-associated GO terms across cancer lineages are Regulation of DNA repair, Negative regulation of gene expression, epigenetic, and Protein-DNA complex organization. Each is linked with ZBTB8B in more than 13 cancer types. Because this analysis shows association rather than direction, both ZBTB8B-to-partner and partner-to-ZBTB8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by ZBTB8B-low versus ZBTB8B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB8B→partner) and Y-score (partner→ZBTB8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of DNA repair →	+0.060	+0.345	<.001	.001	3	14
OVARY	Negative regulation of gene expression, epigenetic →	+0.076	+0.284	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Protein-DNA complex organization →	+0.052	+0.198	<.001	<.001	3	13
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.092	+0.301	<.001	.007	3	13
OESOPHAGUS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.091	+0.301	<.001	.007	3	13
OESOPHAGUS	mRNA splicing, via spliceosome →	+0.091	+0.301	<.001	.007	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,063 associations by consensus.

Regulation of DNA repair by ZBTB8B expression — SOFT_TISSUE

Explore this box plot interactively →