ZBTB8B

Across TCGA cell cohorts, ZBTB8B mutation is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB8B-associated genes across cancer lineages are PMP22, GPR63, and RPS12. Each is linked with ZBTB8B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB8B-to-partner and partner-to-ZBTB8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PMP22 grouped by ZBTB8B-low versus ZBTB8B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB8B→partner) and Y-score (partner→ZBTB8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PMP22 →	+1.467	+3.212	.004	.006	3	1
LARGE_INTESTINE	GPR63 →	+1.095	+3.212	<.001	.006	3	1
LARGE_INTESTINE	RPS12 →	+0.590	+3.212	.001	.006	3	1
LARGE_INTESTINE	FAM120B →	+0.609	+3.212	.005	.006	3	1
LARGE_INTESTINE	TXNDC15 →	+0.614	+3.212	.004	.006	3	1
LARGE_INTESTINE	ZBTB47 →	+0.860	+3.299	.008	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

PMP22 by ZBTB8B expression — LARGE_INTESTINE

Explore this box plot interactively →