ZBTB8A

Across TCGA patient cohorts, ZBTB8A protein abundance is significantly associated with the RNA expression of many other genes, with 836 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBTB8A-associated genes across cancer lineages are PRDX1, SH3RF2, and ABHD11-AS1. Each is linked with ZBTB8A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB8A-to-partner and partner-to-ZBTB8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB8A versus PRDX1 in LSCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB8A→partner) and Y-score (partner→ZBTB8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRDX1 →	-0.801	-0.541	.005	.006	3	2
LUAD	SH3RF2 →	-1.613	-0.636	<.001	<.001	3	2
BRCA	ABHD11-AS1 →	-1.190	-0.575	<.001	.001	3	2
LSCC	CABLES1 →	+0.938	+0.672	.006	.002	3	2
LSCC	ZNF93 →	+1.083	+0.550	.004	.009	3	2
LSCC	ZNF528-AS1 →	+1.033	+0.645	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 836 associations by consensus.

ZBTB8A vs PRDX1 — LSCC

Explore this scatter interactively →