ZBTB8A

Across TCGA cell cohorts, ZBTB8A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,247 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB8A-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Microtubule polymerization, and Positive regulation of organelle assembly. Each is linked with ZBTB8A in more than 11 cancer types. Because this analysis shows association rather than direction, both ZBTB8A-to-partner and partner-to-ZBTB8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Subtelomeric heterochromatin formation grouped by ZBTB8A-low versus ZBTB8A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB8A→partner) and Y-score (partner→ZBTB8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Subtelomeric heterochromatin formation →	+0.126	+0.682	<.001	<.001	3	12
LARGE_INTESTINE	Microtubule polymerization →	+0.120	+0.924	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.062	+0.495	<.001	.002	3	12
LIVER	Positive regulation of cilium assembly →	+0.095	+0.575	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Establishment of mitotic spindle localization →	+0.107	+0.481	.001	.001	3	11
KIDNEY	Positive regulation of mRNA catabolic process →	+0.074	+0.863	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,247 associations by consensus.

Subtelomeric heterochromatin formation by ZBTB8A expression — LIVER

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