ZBTB7B

Across TCGA patient cohorts, ZBTB7B mutation is significantly associated with the RNA expression of many other genes, with 1,217 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB7B-associated genes across cancer lineages are OR4A48P, RNU1-101P, and MOB4P2. Each is linked with ZBTB7B in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB7B-to-partner and partner-to-ZBTB7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4A48P grouped by ZBTB7B-low versus ZBTB7B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB7B→partner) and Y-score (partner→ZBTB7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR4A48P →	+0.032	+4.906	<.001	.001	3	3
BLCA	RNU1-101P →	+0.113	+4.233	<.001	.006	3	3
BLCA	MOB4P2 →	+0.096	+2.610	.004	.008	3	2
SKCM	GTF2F2P2 →	+0.023	+3.385	<.001	.004	3	2
UCEC	COX15 →	+0.319	+1.671	.004	.007	3	2
UCEC	BUB3 →	+0.343	+2.288	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,217 associations by consensus.

OR4A48P by ZBTB7B expression — SKCM

Explore this box plot interactively →