ZBTB7B

Across TCGA cell cohorts, ZBTB7B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,814 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB7B-associated GO terms across cancer lineages are Negative regulation of NK T cell activation, Negative regulation of CD8-positive, alpha-beta T cell differentiation, and Regulation of brown fat cell differentiation. Each is linked with ZBTB7B in more than 17 cancer types. Because this analysis shows association rather than direction, both ZBTB7B-to-partner and partner-to-ZBTB7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of NK T cell activation grouped by ZBTB7B-low versus ZBTB7B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB7B→partner) and Y-score (partner→ZBTB7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of NK T cell activation →	+1.303	+1.313	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.286	+1.448	<.001	<.001	3	16
STOMACH	Regulation of brown fat cell differentiation →	+0.158	+1.604	<.001	<.001	3	16
LUNG_SCLC	Regulation of NK T cell proliferation →	+1.369	+0.737	<.001	<.001	3	15
URINARY_TRACT	Regulation of CD8-positive, alpha-beta T cell differentiation →	+0.191	+0.944	<.001	<.001	3	15
BLOOD_Lymphoma	Cytosolic transport →	+0.071	+1.210	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,814 associations by consensus.

Negative regulation of NK T cell activation by ZBTB7B expression — BONE

Explore this box plot interactively →