ZBTB46

Across TCGA cell cohorts, ZBTB46 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,944 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB46-associated GO terms across cancer lineages are Regulation of RNA splicing, Negative regulation of autophagy, and Establishment of protein localization to plasma membrane. Each is linked with ZBTB46 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZBTB46-to-partner and partner-to-ZBTB46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by ZBTB46-low versus ZBTB46-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB46→partner) and Y-score (partner→ZBTB46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of RNA splicing →	+0.078	+1.052	.003	.006	3	13
BLOOD_Myeloma	Negative regulation of autophagy →	+0.067	+1.127	.002	.002	3	12
SKIN	Establishment of protein localization to plasma membrane →	+0.120	+0.925	<.001	<.001	3	12
STOMACH	Protein targeting to vacuole involved in autophagy →	+0.217	+1.473	.001	.004	3	12
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.093	+1.275	<.001	<.001	3	12
STOMACH	Regulation of nucleotide-excision repair →	+0.162	+1.334	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,944 associations by consensus.

Regulation of RNA splicing by ZBTB46 expression — STOMACH

Explore this box plot interactively →