ZBTB46

Across TCGA cell cohorts, ZBTB46 mutation is significantly associated with the RNA expression of many other genes, with 366 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB46-associated genes across cancer lineages are ANKRD60, OR4F5, and DGAT2L6. Each is linked with ZBTB46 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB46-to-partner and partner-to-ZBTB46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD60 grouped by ZBTB46-low versus ZBTB46-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB46→partner) and Y-score (partner→ZBTB46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ANKRD60 →	+0.020	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR4F5 →	+0.006	+5.977	<.001	.001	3	1
OESOPHAGUS	DGAT2L6 →	+0.006	+4.906	<.001	.006	3	1
BLOOD_Lymphoma	PRY2 →	+0.037	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	PRR23B →	+0.005	+5.247	<.001	.001	3	1
LARGE_INTESTINE	PLA2G3 →	+0.820	+2.125	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 366 associations by consensus.

ANKRD60 by ZBTB46 expression — SOFT_TISSUE

Explore this box plot interactively →