ZBTB45

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBTB45 protein abundance is significantly associated with the RNA expression of many other genes, with 3,572 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZBTB45-associated genes across cancer lineages are TAB2, CACNA1C-AS4, and MYZAP. Each is linked with ZBTB45 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB45-to-partner and partner-to-ZBTB45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB45 versus TAB2 in HNSC, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB45→partner) and Y-score (partner→ZBTB45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCTAB2 →-0.900-1.878.003.00632
BRCACACNA1C-AS4 →+0.114+0.502<.001<.00132
BRCAMYZAP →+1.235+0.479<.001<.00132
UCECKCNE4 →+1.114+0.683.002.00232
UCECZNF469 →+0.768+0.743<.001.00432
BRCACDC73 →-0.921-0.519.006<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,572 associations by consensus.

ZBTB45 vs TAB2 — HNSC

Per-sample scatter of ZBTB45 vs TAB2 in HNSC (Pearson r = -0.64).

Explore this scatter interactively →

Exploration