Across TCGA patient cohorts, ZBTB44 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB44-associated genes across cancer lineages are Epithelial cells, Mesangial cells, and pDC. Each is linked with ZBTB44 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB44-to-partner and partner-to-ZBTB44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB44→partner) and Y-score (partner→ZBTB44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.066	-3.159	.040	.019	3	1
UCEC	Mesangial cells →	-0.037	-2.305	.031	.035	3	1
UCEC	pDC →	+0.092	+2.711	<.001	.003	3	1
UCEC	Macrophages M2 →	+0.010	+2.118	.029	.016	2	1
UCEC	Basophils →	+0.194	+2.000	.011	.032	2	1
SKCM	Endothelial cells →	-0.049	-2.993	.026	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

ZBTB44 survival (RNA) · tumor vs normal (RNA) · all ZBTB44 data types