Across TCGA cell cohorts, ZBTB44 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB44-associated genes across cancer lineages are RASAL3, CHST8, and SLC17A1. Each is linked with ZBTB44 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB44-to-partner and partner-to-ZBTB44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB44→partner) and Y-score (partner→ZBTB44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RASAL3 →	+0.119	+3.617	<.001	.004	3	1
LARGE_INTESTINE	CHST8 →	+0.172	+3.584	<.001	.004	3	1
LARGE_INTESTINE	SLC17A1 →	+0.043	+2.878	<.001	.009	3	1
LARGE_INTESTINE	PLVAP →	+0.258	+3.539	<.001	.004	3	1
LARGE_INTESTINE	SLCO1C1 →	+0.598	+4.035	<.001	<.001	3	1
LARGE_INTESTINE	ECE2 →	+0.282	+3.376	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

ZBTB44 survival (RNA) · tumor vs normal (RNA) · all ZBTB44 data types