ZBTB43

Across TCGA patient cohorts, ZBTB43 mutation is significantly associated with the RNA expression of many other genes, with 3,079 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB43-associated genes across cancer lineages are COPS3, WRAP53, and CRK. Each is linked with ZBTB43 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB43-to-partner and partner-to-ZBTB43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPS3 grouped by ZBTB43-low versus ZBTB43-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB43→partner) and Y-score (partner→ZBTB43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	COPS3 →	+0.682	+3.525	<.001	.002	3	3
COAD	WRAP53 →	+0.518	+3.498	<.001	.002	3	3
COAD	CRK →	+0.362	+2.598	.008	.006	3	3
COAD	SF3B5 →	+0.435	+2.625	.008	.005	3	3
COAD	NAA38 →	+0.851	+3.713	<.001	<.001	3	3
UCEC	LINC01871 →	+0.851	+1.736	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,079 associations by consensus.

COPS3 by ZBTB43 expression — COAD

Explore this box plot interactively →