ZBTB43

Across TCGA cell cohorts, ZBTB43 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,208 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZBTB43-associated GO terms across cancer lineages are Regulation of vacuole organization, Negative regulation of macroautophagy, and Positive regulation of autophagosome assembly. Each is linked with ZBTB43 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZBTB43-to-partner and partner-to-ZBTB43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vacuole organization grouped by ZBTB43-low versus ZBTB43-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB43→partner) and Y-score (partner→ZBTB43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of vacuole organization →	+0.087	+1.109	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of macroautophagy →	+0.099	+1.130	<.001	<.001	3	14
STOMACH	Positive regulation of autophagosome assembly →	+0.095	+0.937	<.001	<.001	3	14
BLOOD_Leukemia	Negative regulation of DNA-templated transcription initiation →	+0.123	+0.828	<.001	.001	3	14
BLOOD_Leukemia	Negative regulation of transcription initiation by RNA polymerase II →	+0.123	+0.828	<.001	.001	3	14
OESOPHAGUS	Protein modification by small protein removal →	+0.047	+1.098	.005	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,208 associations by consensus.

Regulation of vacuole organization by ZBTB43 expression — STOMACH

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