ZBTB42

Across TCGA patient cohorts, ZBTB42 protein abundance is significantly associated with the RNA expression of many other genes, with 269 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZBTB42-associated genes across cancer lineages are SLC25A1, KDM4C, and KANK1. Each is linked with ZBTB42 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB42-to-partner and partner-to-ZBTB42 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB42 versus SLC25A1 in BRCA, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB42→partner) and Y-score (partner→ZBTB42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC25A1 →	-1.055	-0.576	.001	.001	3	1
BRCA	KDM4C →	+1.066	+0.529	<.001	.004	3	1
BRCA	KANK1 →	+1.434	+0.636	<.001	.001	3	1
BRCA	ARHGAP21 →	+1.477	+0.733	.002	.002	3	1
BRCA	PIGL →	+1.118	+0.624	.001	.002	3	1
BRCA	HLF →	+0.810	+0.618	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 269 associations by consensus.

ZBTB42 vs SLC25A1 — BRCA

Explore this scatter interactively →