ZBTB42

Across TCGA cell cohorts, ZBTB42 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,788 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZBTB42-associated GO terms across cancer lineages are Mitochondrion-endoplasmic reticulum membrane tethering, Negative regulation of RNA splicing, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ZBTB42 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZBTB42-to-partner and partner-to-ZBTB42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrion-endoplasmic reticulum membrane tethering grouped by ZBTB42-low versus ZBTB42-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB42→partner) and Y-score (partner→ZBTB42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Mitochondrion-endoplasmic reticulum membrane tethering →	+0.165	+1.592	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of RNA splicing →	+0.099	+0.858	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.139	+0.940	<.001	<.001	3	12
BLOOD_Myeloma	Regulation of protein localization to endoplasmic reticulum →	+0.112	+1.002	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.125	+0.889	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.144	+0.873	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,788 associations by consensus.

Mitochondrion-endoplasmic reticulum membrane tethering by ZBTB42 expression — BREAST

Explore this box plot interactively →