ZBTB42

Across TCGA cell cohorts, ZBTB42 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB42-associated genes across cancer lineages are ITGAD, BPIFB6, and OR10W1. Each is linked with ZBTB42 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB42-to-partner and partner-to-ZBTB42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGAD grouped by ZBTB42-low versus ZBTB42-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB42→partner) and Y-score (partner→ZBTB42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.009	+2.925	.003	.007	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	SAMD7 →	+0.014	+2.878	.002	.009	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	LRRC3C →	+0.307	+3.099	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ITGAD by ZBTB42 expression — LARGE_INTESTINE

Explore this box plot interactively →