ZBTB41

Across TCGA cell cohorts, ZBTB41 mutation is significantly associated with the RNA expression of many other genes, with 246 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB41-associated genes across cancer lineages are ACTRT1, OR2T10, and SLC22A6. Each is linked with ZBTB41 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB41-to-partner and partner-to-ZBTB41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTRT1 grouped by ZBTB41-low versus ZBTB41-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB41→partner) and Y-score (partner→ZBTB41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	ACTRT1 →	+0.041	+3.514	<.001	.008	3	2
LUNG_NSCLC_LUSC	OR2T10 →	+0.067	+3.584	.001	.003	3	2
LUNG_NSCLC_LUSC	SLC22A6 →	+0.016	+3.584	.003	.003	3	2
LUNG_NSCLC_LUSC	PSMB11 →	+0.015	+3.514	.001	.008	3	2
LARGE_INTESTINE	LPGAT1 →	+0.640	+3.502	<.001	.001	3	2
SKIN	OR52J3 →	+0.032	+3.700	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 246 associations by consensus.

ACTRT1 by ZBTB41 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →