ZBTB39

Across TCGA patient cohorts, ZBTB39 mutation is significantly associated with the RNA expression of many other genes, with 3,121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB39-associated genes across cancer lineages are ABHD15-AS1, LINC01291, and LINC00458. Each is linked with ZBTB39 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB39-to-partner and partner-to-ZBTB39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABHD15-AS1 grouped by ZBTB39-low versus ZBTB39-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB39→partner) and Y-score (partner→ZBTB39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ABHD15-AS1 →	+0.136	+2.546	<.001	.001	3	2
UCEC	LINC01291 →	-0.721	-2.087	<.001	<.001	3	2
UCEC	LINC00458 →	+0.145	+1.413	<.001	.001	3	2
UCEC	CSTF3-DT →	+0.117	+1.924	.002	<.001	3	2
UCEC	RNA5SP415 →	+0.290	+1.614	.002	.004	3	2
UCEC	ATP2A1-AS1 →	+0.740	+2.470	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,121 associations by consensus.

ABHD15-AS1 by ZBTB39 expression — SKCM

Explore this box plot interactively →