ZBTB37

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZBTB37 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZBTB37-associated genes across cancer lineages are KRT73, SPESP1, and SPINK14. Each is linked with ZBTB37 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB37-to-partner and partner-to-ZBTB37 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB37→partner) and Y-score (partner→ZBTB37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEKRT73 →+0.070+3.196<.001.00731
LARGE_INTESTINESPESP1 →+0.747+3.643<.001.00531
LUNG_NSCLC_LUADSPINK14 →+0.264+4.662<.001.00531
LUNG_NSCLC_LUADCD300LD →+0.108+4.947<.001.00131
LUNG_NSCLC_LUADSCYGR2 →+0.079+4.544.008.00331
OVARYTLE7 →+0.006+5.807<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration