ZBTB34

Across TCGA patient cohorts, ZBTB34 mutation is significantly associated with the RNA expression of many other genes, with 4,411 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB34-associated genes across cancer lineages are TUBGCP5, MED8, and CHCHD4. Each is linked with ZBTB34 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB34-to-partner and partner-to-ZBTB34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBGCP5 grouped by ZBTB34-low versus ZBTB34-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB34→partner) and Y-score (partner→ZBTB34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBGCP5 →	+0.318	+2.180	.002	.001	3	3
UCEC	MED8 →	+0.277	+2.279	<.001	<.001	3	3
UCEC	CHCHD4 →	+0.352	+2.346	<.001	<.001	3	3
UCEC	RPUSD4 →	+0.267	+1.938	.009	.001	3	3
UCEC	NIPA1 →	+0.709	+1.606	<.001	<.001	3	3
COAD	PLRG1 →	+0.372	+3.342	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,411 associations by consensus.

TUBGCP5 by ZBTB34 expression — UCEC

Explore this box plot interactively →