ZBTB34

Across TCGA cell cohorts, ZBTB34 protein abundance is significantly associated with the go_rna of many other GO terms, with 787 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ZBTB34-associated GO terms across cancer lineages are Regulation of relaxation of cardiac muscle, Positive regulation of substrate adhesion-dependent cell spreading, and Glucocorticoid metabolic process. Each is linked with ZBTB34 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZBTB34-to-partner and partner-to-ZBTB34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of relaxation of cardiac muscle grouped by ZBTB34-low versus ZBTB34-high in OESOPHAGUS.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB34→partner) and Y-score (partner→ZBTB34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of relaxation of cardiac muscle →	-1.360	-4.000	.002	.001	3	4
BLOOD_Leukemia	Positive regulation of substrate adhesion-dependent cell spreading →	+0.073	+0.827	.003	.001	3	4
OVARY	Glucocorticoid metabolic process →	-0.408	-1.587	<.001	.002	3	3
LUNG_NSCLC_LUAD	Regulation of membrane lipid distribution →	+0.076	+2.993	.003	.002	3	3
OESOPHAGUS	Iodide transport →	+0.234	+5.013	.003	.003	3	3
OESOPHAGUS	Regulation of CD8-positive, alpha-beta T cell extravasation →	+0.426	+3.999	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 787 associations by consensus.

Regulation of relaxation of cardiac muscle by ZBTB34 expression — OESOPHAGUS

Explore this box plot interactively →