ZBTB32

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBTB32 mutation is significantly associated with the RNA expression of many other genes, with 771 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB32-associated genes across cancer lineages are RN7SL248P, RN7SL447P, and OR5D3P. Each is linked with ZBTB32 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZBTB32-to-partner and partner-to-ZBTB32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by ZBTB32-low versus ZBTB32-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB32→partner) and Y-score (partner→ZBTB32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.082+3.722<.001.00134
CESCRN7SL447P →+0.163+5.201<.001.00732
COADOR5D3P →+0.046+4.595.004.00432
COADUBE2V1P3 →+0.096+4.399<.001.00632
COADRPS29P2 →+0.363+5.831<.001<.00132
SKCMUGT1A3 →+0.011+3.771<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 771 associations by consensus.

RN7SL248P by ZBTB32 expression — UCEC

Box plot of RN7SL248P in ZBTB32-low vs ZBTB32-high samples in UCEC.

Explore this box plot interactively →

Exploration