Across TCGA patient cohorts, ZBTB3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,612 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZBTB3-associated genes across cancer lineages are RERG, PAQR3, and C14orf132. Each is linked with ZBTB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB3-to-partner and partner-to-ZBTB3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB3→partner) and Y-score (partner→ZBTB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RERG →	+1.850	+0.309	<.001	<.001	3	2
LSCC	PAQR3 →	-0.548	-0.343	<.001	.001	3	2
LUAD	C14orf132 →	+0.709	+0.537	.001	.002	3	2
GBM	MICAL3 →	-0.588	-0.358	<.001	.003	3	2
OV	ZDHHC2 →	+1.297	+0.524	.008	.006	3	2
OV	ETS2 →	+0.931	+0.407	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,612 associations by consensus.

Exploration

ZBTB3 survival (RNA) · tumor vs normal (RNA) · all ZBTB3 data types