Across TCGA patient cohorts, ZBTB3 mutation is significantly associated with the RNA expression of many other genes, with 607 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB3-associated genes across cancer lineages are RNU1-62P, RNU6-782P, and RNA5SP478. Each is linked with ZBTB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB3-to-partner and partner-to-ZBTB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB3→partner) and Y-score (partner→ZBTB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU1-62P →	+0.164	+4.315	<.001	.007	3	3
BRCA	RNU6-782P →	+0.885	+4.800	<.001	.006	3	2
HNSC	RNA5SP478 →	+0.284	+4.424	<.001	.008	3	2
LUAD	LINC02692 →	+0.089	+3.643	.006	.008	3	2
LUAD	RNU6-466P →	+0.614	+4.178	.004	.002	3	2
LUAD	BTG3P1 →	+0.050	+4.444	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 607 associations by consensus.

Exploration

ZBTB3 survival (RNA) · tumor vs normal (RNA) · all ZBTB3 data types