ZBTB26

Across TCGA patient cohorts, ZBTB26 protein abundance is significantly associated with the RNA expression of many other genes, with 575 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBTB26-associated genes across cancer lineages are PNPLA5, EEF1A2, and SPEF1. Each is linked with ZBTB26 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB26-to-partner and partner-to-ZBTB26 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB26 versus PNPLA5 in LSCC, with a Pearson correlation of 0.91.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB26→partner) and Y-score (partner→ZBTB26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PNPLA5 →	+0.816	+1.373	.004	.006	2	1
LSCC	EEF1A2 →	+5.511	+1.373	<.001	.006	2	1
LSCC	SPEF1 →	+1.336	+1.373	.006	.006	2	1
LSCC	TTI1 →	+0.870	+1.373	.005	.006	2	1
LSCC	CST9L →	+0.205	+1.373	.008	.006	2	1
LSCC	ZNF516 →	+1.000	+1.373	.006	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 575 associations by consensus.

ZBTB26 vs PNPLA5 — LSCC

Explore this scatter interactively →