ZBTB26

Across TCGA cell cohorts, ZBTB26 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB26-associated genes across cancer lineages are MCHR2, FAM71B, and OR56A1. Each is linked with ZBTB26 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB26-to-partner and partner-to-ZBTB26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MCHR2 grouped by ZBTB26-low versus ZBTB26-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB26→partner) and Y-score (partner→ZBTB26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MCHR2 →	+0.027	+4.684	<.001	.002	3	1
LARGE_INTESTINE	FAM71B →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OR56A1 →	+0.012	+4.467	.005	.004	3	1
LARGE_INTESTINE	OR13G1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	IL31 →	+0.038	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR1C1 →	+0.090	+4.684	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

MCHR2 by ZBTB26 expression — LARGE_INTESTINE

Explore this box plot interactively →