ZBTB25

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBTB25 protein abundance is significantly associated with the RNA expression of many other genes, with 8,509 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZBTB25-associated genes across cancer lineages are HUS1B, RLN1, and SLC35D2. Each is linked with ZBTB25 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB25-to-partner and partner-to-ZBTB25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB25 versus HUS1B in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB25→partner) and Y-score (partner→ZBTB25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMHUS1B →+0.347+0.605.002<.00132
LUADRLN1 →+0.396+0.536.005.00332
BRCASLC35D2 →+0.469+0.715.001<.00132
BRCAMSS51 →+1.021+1.107<.001<.00132
BRCACLK3 →+0.551+0.728<.001<.00132
LUADOSER1-DT →+0.592+0.748.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,509 associations by consensus.

ZBTB25 vs HUS1B — GBM

Per-sample scatter of ZBTB25 vs HUS1B in GBM (Pearson r = 0.38).

Explore this scatter interactively →

Exploration