ZBTB22

Across TCGA cell cohorts, ZBTB22 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZBTB22-associated genes across cancer lineages are KRTAP10-5, PRR23D1, and PRR23D2. Each is linked with ZBTB22 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB22-to-partner and partner-to-ZBTB22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-5 grouped by ZBTB22-low versus ZBTB22-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB22→partner) and Y-score (partner→ZBTB22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	PRR23D1 →	+0.018	+5.044	<.001	.001	1	1
LUNG_NSCLC_LUAD	PRR23D2 →	+0.018	+5.044	<.001	.001	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

KRTAP10-5 by ZBTB22 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →