ZBTB20-AS5

Across TCGA pan-cancer cohorts, ZBTB20-AS5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ZBTB20-AS5’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ZBTB20-AS5 RNA is repressed in tumor relative to normal tissue. In most cancer types ZBTB20-AS5 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LUSC, and READ are the cancer types where ZBTB20-AS5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZBTB20-AS5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.089	<.001	6	view →
LUSC	All	III,IV	−0.063	.003	5	view →
READ	Female	All	−0.050	.007	2	view →
UCEC	All	All	−0.041	.036	2	view →
KICH	Female	All	−0.046	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ZBTB20-AS5–THCA

Open the THCA breakdown →