ZBTB20-AS4

Across TCGA pan-cancer cohorts, ZBTB20-AS4 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ZBTB20-AS4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZBTB20-AS4 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZBTB20-AS4 expression acts as an unfavorable survival marker, although some lineages such as KIRC and MESO show a favorable association.

KIRC, MESO, and LGG are the cancer types where ZBTB20-AS4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.716	0.539	<.001	114	view →
MESO	OS	Quartile	All	0.567	0.237	<.001	56	view →
LGG	DFS	Median	All	0.835	0.625	<.001	53	view →
LIHC	OS	Median	III,IV	0.486	0.211	<.001	40	view →
THCA	OS	Median	II,III,IV	0.550	1.000	.003	29	view →
CESC	DFS	Median	III,IV	0.225	0.630	.007	22	view →
HNSC	DFS	Quartile	All	0.779	0.668	.006	22	view →
ACC	OS	Median	II,III,IV	0.699	0.461	.016	21	view →
BRCA	OS	Median	All	0.977	0.947	.001	20	view →
PRAD	DFS	Tertile	All	0.893	0.720	.003	16	view →
SKCM	OS	Median	All	0.377	0.294	.002	14	view →
GBM	DFS	Quartile	All	0.336	0.204	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ZBTB20-AS4–KIRC (DFS)

Open the KIRC breakdown →