ZBTB18

Across TCGA patient cohorts, ZBTB18 mutation is significantly associated with the RNA expression of many other genes, with 2,936 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB18-associated genes across cancer lineages are RN7SL98P, PAFAH1B2, and RNU6-1318P. Each is linked with ZBTB18 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB18-to-partner and partner-to-ZBTB18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL98P grouped by ZBTB18-low versus ZBTB18-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB18→partner) and Y-score (partner→ZBTB18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL98P →	+0.098	+2.993	.005	.002	3	3
UCEC	PAFAH1B2 →	+0.367	+3.523	.003	.002	3	3
LUAD	RNU6-1318P →	+0.688	+4.319	<.001	.007	3	3
SARC	IGHVIII-5-2 →	+0.759	+5.005	.002	.009	3	3
CESC	RNU6-960P →	+0.134	+4.569	<.001	<.001	3	2
CESC	RNU6-886P →	+0.354	+3.056	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,936 associations by consensus.

RN7SL98P by ZBTB18 expression — COAD

Explore this box plot interactively →