ZBTB17

Across TCGA patient cohorts, ZBTB17 mutation is significantly associated with the RNA expression of many other genes, with 1,984 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB17-associated genes across cancer lineages are RN7SL577P, RPL22P5, and RNA5SP192. Each is linked with ZBTB17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB17-to-partner and partner-to-ZBTB17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL577P grouped by ZBTB17-low versus ZBTB17-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB17→partner) and Y-score (partner→ZBTB17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SL577P →	+0.200	+4.952	<.001	.002	3	2
CESC	RPL22P5 →	+0.154	+5.103	<.001	.008	3	2
HNSC	RNA5SP192 →	+0.313	+5.608	<.001	.002	3	2
BLCA	RNA5SP451 →	+0.188	+5.311	<.001	.001	3	2
BLCA	MIR3688-1 →	+0.232	+4.296	<.001	.006	3	2
SKCM	RNU1-134P →	+0.280	+4.156	.006	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,984 associations by consensus.

RN7SL577P by ZBTB17 expression — HNSC

Explore this box plot interactively →