Across TCGA pan-cancer cohorts, ZBTB14 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZBTB14 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZBTB14 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ZBTB14 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD and CCRCC are the cancer types where ZBTB14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.950	0.617	.003	12	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: ZBTB14 tumor-vs-normal RNA expression · all ZBTB14 data types