Across TCGA patient cohorts, ZBTB14 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB14-associated genes across cancer lineages are Cyclin-E2, Cyclin-B1, and EGFR_pY1068. Each is linked with ZBTB14 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB14-to-partner and partner-to-ZBTB14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB14→partner) and Y-score (partner→ZBTB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Cyclin-E2 →	+0.240	+3.025	.036	.018	3	3
UCEC	Cyclin-B1 →	+0.578	+1.502	.005	.030	3	3
UCEC	EGFR_pY1068 →	-0.208	-1.847	.023	.008	3	2
UCEC	HSP70 →	-0.291	-2.449	.048	.019	3	2
UCEC	Annexin-1 →	+0.497	+2.479	.010	.010	3	2
UCEC	Caspase-7-cleavedD198 →	+0.689	+2.341	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

ZBTB14 survival (RNA) · tumor vs normal (RNA) · all ZBTB14 data types