Across TCGA patient cohorts, ZBTB12 protein abundance is significantly associated with the RNA expression of many other genes, with 4,450 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBTB12-associated genes across cancer lineages are FLVCR2, MRPS14, and LINC01342. Each is linked with ZBTB12 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB12-to-partner and partner-to-ZBTB12 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB12→partner) and Y-score (partner→ZBTB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FLVCR2 →	-0.461	-0.487	.009	.002	3	3
BRCA	MRPS14 →	+0.576	+0.620	<.001	.001	3	3
BRCA	LINC01342 →	+0.545	+0.582	.004	.001	3	3
LSCC	CYTH4 →	-0.623	-0.451	<.001	<.001	3	2
BRCA	XBP1 →	+1.399	+0.572	.008	.006	3	2
LSCC	NCF4 →	-0.675	-0.567	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,450 associations by consensus.

Exploration

ZBTB12 survival (RNA) · tumor vs normal (RNA) · all ZBTB12 data types