ZBTB12

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBTB12 mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB12-associated genes across cancer lineages are NDUFS5P6, MIR4794, and SNORD112. Each is linked with ZBTB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB12-to-partner and partner-to-ZBTB12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB12→partner) and Y-score (partner→ZBTB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCNDUFS5P6 →+0.367+4.539<.001.00832
CESCMIR4794 →+0.309+6.164<.001<.00132
SKCMSNORD112 →+0.291+4.614.005.00632
LUADMORF4L1P6 →+0.139+7.930<.001.00832
CESCVDAC1P12 →+0.045+4.969<.001.00432
COADZMYND10-AS1 →+0.233+4.081<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

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