Q-omics provides the consensus-scored VDAC1P12 profile across patient tissues and cancer cell-line models. VDAC1P12 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in PAAD. Additionally, VDAC1P12 RNA expression shows 5,476 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight PAAD, and GBM as cancer lineages where VDAC1P12 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes VDAC1P12 survival associations across molecular data types. VDAC1P12 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

VDAC1P12 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	LIHC (72)	view →

This table ranks reproducible VDAC1P12 RNA expression–survival associations across cancer types. High VDAC1P12 expression shows unfavorable associations in PAAD, LIHC, ESCA, SKCM, LUAD and HNSC. The PAAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify PAAD as the clearest survival context for VDAC1P12 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.028	0.614	<.001	72	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.716	<.001	72	view →
ESCA	DFS	Tertile	All	0.226	0.808	.001	63	view →
SKCM	OS	Tertile	III,IV	0.216	0.721	.001	30	view →
LUAD	OS	Tertile	IV	0.114	0.560	.038	18	view →
HNSC	OS	Tertile	II,III,IV	0.191	0.601	.034	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

VDAC1P12-PAAD (OS)

Kaplan–Meier survival curve for VDAC1P12 RNA expression in PAAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with VDAC1P12 in patient tissues and cancer cell lines. In patient samples, VDAC1P12 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	5,476	GBM (3301)	view →
Function (RNA)	4,892	STAD (4389)	view →