ZBTB11

Across TCGA cell cohorts, ZBTB11 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ZBTB11-associated genes across cancer lineages are GABRA6, AVP, and FASLG. Each is linked with ZBTB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB11-to-partner and partner-to-ZBTB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GABRA6 grouped by ZBTB11-low versus ZBTB11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB11→partner) and Y-score (partner→ZBTB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GABRA6 →	+0.372	+3.345	<.001	.007	3	2
LARGE_INTESTINE	AVP →	+0.056	+3.632	<.001	.003	3	1
OVARY	FASLG →	+0.126	+3.714	.001	.004	3	1
OVARY	MYBPC3 →	+0.019	+3.592	.009	.006	3	1
OVARY	MROH2B →	+0.035	+3.754	<.001	.002	3	1
OVARY	MS4A10 →	+0.008	+4.196	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

GABRA6 by ZBTB11 expression — LARGE_INTESTINE

Explore this box plot interactively →