ZBTB11-AS1

Across TCGA pan-cancer cohorts, ZBTB11-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ZBTB11-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher ZBTB11-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZBTB11-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and ESCA show a favorable association.

KICH, UVM, and UCEC are the cancer types where ZBTB11-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.282	1.000	.002	94	view →
UVM	DFS	Median	II,III,IV	0.743	0.378	.001	56	view →
UCEC	DFS	Median	All	0.567	0.717	<.001	42	view →
LIHC	DFS	Tertile	All	0.436	0.627	<.001	39	view →
ESCA	OS	Median	IV	0.698	0.222	.006	27	view →
ACC	DFS	Quartile	All	0.269	0.813	.001	26	view →
READ	DFS	Median	II,III,IV	0.763	0.249	.004	14	view →
LUSC	DFS	Median	All	0.797	0.695	.003	13	view →
COAD	DFS	Quartile	IV	0.210	0.661	.001	9	view →
OV	OS	Median	IV	0.492	0.283	.015	8	view →
MESO	DFS	Tertile	IV	0.449	0.738	.041	6	view →
CHOL	OS	Quartile	All	1.000	0.577	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ZBTB11-AS1–KICH (DFS)

Open the KICH breakdown →