ZBTB11-AS1

Across TCGA pan-cancer cohorts, ZBTB11-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ZBTB11-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where ZBTB11-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZBTB11-AS1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

LIHC, THCA, and HNSC are the cancer types where ZBTB11-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZBTB11-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+0.808	<.001	9	view →
THCA	All	IV	−0.659	<.001	9	view →
HNSC	Male	IV	+0.940	<.001	8	view →
KICH	Male	All	−0.780	<.001	7	view →
LUSC	Male	All	+0.455	<.001	5	view →
KIRC	Male	II,III,IV	−0.276	.004	4	view →
CHOL	All	All	+1.211	<.001	3	view →
STAD	All	II,III,IV	+0.310	.013	3	view →
PRAD	All	All	+0.122	.040	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ZBTB11-AS1–LIHC

Open the LIHC breakdown →