ZBTB1

Across TCGA patient cohorts, ZBTB1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,574 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZBTB1-associated genes across cancer lineages are MTHFD1, DLST, and RNU6-570P. Each is linked with ZBTB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZBTB1-to-partner and partner-to-ZBTB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB1 versus MTHFD1 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB1→partner) and Y-score (partner→ZBTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTHFD1 →	+0.398	+0.284	<.001	<.001	3	3
BRCA	DLST →	+0.413	+0.273	<.001	<.001	3	3
PDAC	RNU6-570P →	-1.235	-0.328	.002	.005	3	3
GBM	NAGPA-AS1 →	-0.307	-0.277	<.001	<.001	3	3
UCEC	SYNE2 →	+0.570	+0.150	.006	.008	2	4
LUAD	SRSF5 →	+0.330	+0.122	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,574 associations by consensus.

ZBTB1 vs MTHFD1 — GBM

Explore this scatter interactively →