ZBP1

Across TCGA patient cohorts, ZBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,102 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBP1-associated genes across cancer lineages are MAP4K1, CD79A, and BIN2. Each is linked with ZBP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZBP1-to-partner and partner-to-ZBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBP1 versus MAP4K1 in UCEC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBP1→partner) and Y-score (partner→ZBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP4K1 →	+1.448	+0.925	.001	.004	3	5
HNSC	CD79A →	+2.393	+0.701	<.001	<.001	3	5
UCEC	BIN2 →	+1.117	+0.745	.008	.001	3	5
UCEC	LY9 →	+1.391	+0.934	.003	.006	3	5
LSCC	FCRLA →	+0.778	+0.542	<.001	<.001	3	5
LUAD	BLK →	+0.880	+0.368	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,102 associations by consensus.

ZBP1 vs MAP4K1 — UCEC

Explore this scatter interactively →