Across TCGA patient cohorts, ZBED6CL mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBED6CL-associated genes across cancer lineages are p62 Lck ligand, Tuberin, and EGFR_pY1068. Each is linked with ZBED6CL in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBED6CL-to-partner and partner-to-ZBED6CL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED6CL→partner) and Y-score (partner→ZBED6CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	p62 Lck ligand →	+0.529	+3.169	.011	.019	3	2
UCEC	Tuberin →	+0.323	+2.179	.010	.034	3	2
UCEC	EGFR_pY1068 →	-0.316	-3.321	.006	.010	2	2
UCEC	FOXO3a_pS318_S321 →	-0.158	-3.160	.006	.019	3	1
UCEC	IGFBP2 →	-0.682	-3.000	.024	.036	2	2
UCEC	JNK2 →	+0.356	+3.179	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

ZBED6CL survival (RNA) · tumor vs normal (RNA) · all ZBED6CL data types