ZBED6CL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZBED6CL mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZBED6CL-associated genes across cancer lineages are LRIT2, RBMY1J, and MEIKIN. Each is linked with ZBED6CL in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBED6CL-to-partner and partner-to-ZBED6CL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED6CL→partner) and Y-score (partner→ZBED6CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINLRIT2 →+0.029+5.415<.001.00431
SKINRBMY1J →+0.006+4.977<.001.00731
SKINMEIKIN →+0.019+5.415<.001.00431
SKINOR5V1 →+0.016+4.977<.001.00731
BLOOD_LeukemiaOR51T1 →+0.071+4.922<.001.00931
BLOOD_LeukemiaGSG1L2 →+0.058+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration