ZBED6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBED6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,457 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBED6-associated genes across cancer lineages are ACOT13, FCGR3B, and CXCR1. Each is linked with ZBED6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBED6-to-partner and partner-to-ZBED6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBED6 versus ACOT13 in GBM, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED6→partner) and Y-score (partner→ZBED6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMACOT13 →-0.494-0.534.003.00633
LSCCFCGR3B →+1.304+0.643<.001<.00132
LSCCCXCR1 →+0.869+0.642<.001<.00132
LSCCADGRG3 →+0.677+0.669<.001<.00132
LUADGK-IT1 →+0.842+0.802<.001<.00132
LUADMIR7152 →+1.093+0.686.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,457 associations by consensus.

ZBED6 vs ACOT13 — GBM

Per-sample scatter of ZBED6 vs ACOT13 in GBM (Pearson r = -0.61).

Explore this scatter interactively →

Exploration